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DAILY NEWS ANALYSIS

  • 28 October, 2020

  • 4 Min Read

Analysis of Indian Genes

Analysis of Indian Genes

What is the news?

  • Recently, the results from the computation analysis of the 1029 sequenced genomes from India were published in the scientific journal, Nucleic Acid Research.
  • The analysis has found that out of 55,898,122 single nucleotide variants in India 18,016,257 (32.23%) variants are unique and found only in the samples sequenced from India.
  • This emphasizes the need for an India centric population genomic initiative.
  • The analysis was carried out by CSIR constituent labs, Institute of Genomics and Integrative Biology (IGIB), Delhi and Centre for Cellular and Molecular Biology (CCMB), Hyderabad.

IndiGenomes Resource Database

  • It encompasses the genomic data from over 1000 whole genome sequences sequenced from across India as part of the IndiGen programme and represents diverse geographies and ethnicities.
  • The IndiGen Programme was launched in April 2019, under which genome sequencing of 1029 self-declared healthy Indians drawn from across the country has been completed.
  • Its objective was to enable genetic epidemiology and develop public health technologies applications using population genome data.
  • The resource provides access to over 55 million genetic variants representing the contemporary Indian population with an objective to classify variants involved in mendelian disorders and improve precision medicine outcomes.
  • Mendelian disorder is a type of genetic disorder, resulting due to alterations in a gene or due to abnormalities in the genome.

Source: PIB


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