Analysis of Indian Genes

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Recently, the results from the computation analysis of the 1029 sequenced genomes from India were published in the scientific journal, Nucleic Acid Research.
The analysis has found that out of 55,898,122 single nucleotide variants in India 18,016,257 (32.23%) variants are unique and found only in the samples sequenced from India.
This emphasizes the need for an India centric population genomic initiative.
The analysis was carried out by CSIR constituent labs, Institute of Genomics and Integrative Biology (IGIB), Delhi and Centre for Cellular and Molecular Biology (CCMB), Hyderabad.

IndiGenomes Resource Database

It encompasses the genomic data from over 1000 whole genome sequences sequenced from across India as part of the IndiGen programme and represents diverse geographies and ethnicities.
The IndiGen Programme was launched in April 2019, under which genome sequencing of 1029 self-declared healthy Indians drawn from across the country has been completed.
Its objective was to enable genetic epidemiology and develop public health technologies applications using population genome data.
The resource provides access to over 55 million genetic variants representing the contemporary Indian population with an objective to classify variants involved in mendelian disorders and improve precision medicine outcomes.
The mendelian disorder is a type of genetic disorder, resulting due to alterations in a gene or abnormalities in the genome.

Source: PIB

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