×

UPSC Courses

DNA banner

DAILY NEWS ANALYSIS

  • 05 October, 2020

  • 3 Min Read

Feluda Test

Feluda Test

  • Feluda is the acronym for FNCAS9 Editor Linked Uniform Detection Assay.
  • It is an accurate and low-cost paper-based test strip to detect Covid-19 and can deliver a result in 45 minutes.
  • Developed by the Council of Scientific and Industrial Research (CSIR) and Tata Group.

How does it work?

  • It uses indigenously developed CRISPR gene-editing technology to identify and target the genetic material of SARS-CoV2, the virus that causes Covid-19.

Significance:

  • According to CSIR, the test matches the accuracy levels of RT-PCR tests.
  • ‘Feluda’ is also the world’s first diagnostic test to deploy a specially adapted Cas9 protein to successfully detect the virus.

Source: TH

GS-III :
  • 12 May, 2020

  • 4 Min Read

Feluda Test

Feluda Test

Part of: GS-III- S&T (PT-MAINS-PERSONALITY TEST)

Recently, the Council of Scientific and Industrial Research’s Institute of Genomics and Integrative Biology (CSIR-IGIB) has developed India’s first paper strip test for Covid-19 namely, ‘Feluda’.

Imp Points

  • Description:
    • The Feluda is a paper strip test that detects the coronavirus in an hour.
    • Feluda is an acronym for FNCAS9 Editor Linked Uniform Detection.
    • It is expected to help to fulfil an urgent need of the rapid testing in India.
    • It is the first such indigenous test kit to be developed in India based on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology.
      • CRISPR is a gene editing technology, which replicates natural defence mechanisms in bacteria to fight virus attacks, using a special protein called Cas9.
      • CRISPR-Cas9 technology behaves like a cut-and-paste mechanism on DNA strands that contain genetic information. The specific location of the genetic codes that need to be changed, or edited, is identified on the DNA strand, and then, using the Cas9 protein, which acts like a pair of scissors, that location is cut off from the strand.
      • A DNA strand, when broken, has a natural tendency to repair itself. Scientists intervene during this auto-repair process, supplying the desired sequence of genetic codes that binds itself with the broken DNA strand.
  • Comparison to the RT-PCR Test:
    • Working Principle: The Feluda test uses the gene-editing tool-Crispr-Cas9 to target and identify genomic sequences of the novel coronavirus in suspected individual samples.
      • RT-PCR test (Reverse Transcription Polymerase Chain Reaction) detects the virus genetic material, which is the Ribonucleic acid (RNA) .
    • Cost: The Feluda test will cost less than Rs.500 compared to Rs. 4500 for the real-time PCR test which is currently being used for Covid-19 diagnosis in India.
    • Required Medical Machinery: The Feluda test also does not rely on expensive real-time PCR machines for RNA isolation, DNA conversion, and amplification which are already in limited supply in the country.

Source: FE


Report On Amazon Rainforest

Report On Amazon Rainforest Recent research from the World Wildlife Fund (WWF) titled "Living Amazon Report" 2022 claims that 35% of the rainforest has either completely disappeared or is severely degraded. The study was presented at the United Nations Framework Convention on Climate Change's 27th Conference of Parties (COP27)

Global Offshore Wind Alliance (GOWA)

Global Offshore Wind Alliance (GOWA) At COP27, nine more nations just joined the Global Offshore Wind Alliance. Belgium, Colombia, Germany, Ireland, Japan, the Netherlands, Norway, the UK, and the US are the nine new nations. Australia declares its membership in the international offshore wind alliance. What is GOWA, or the Globa

About G-20 Summit 2022, in Egypt

About G-20 Summit 2022, in Egypt The Indonesian G20 presidency recently hosted the 17th annual G-20 conference in Bali with the motto "Recover Together, Recover Stronger." As of right now, India is in charge of the G20 presidency, and the 18th summit will take place there in 2023. What were the Summit's results? Russia

The Artemis I: Moon Mission by NASA

The Artemis I: Moon Mission by NASA On November 16, 2022, the National Aeronautics and Space Administration (NASA) successfully launched its unmanned Artemis I mission to the Moon. The Space Launch System (SLS) rocket has launched from the Kennedy Space Centre in Cape Canaveral, Florida after several delays brought on by unforeseen te

Global Health and Climate Change

Global Health and Climate Change Reliance on fossil fuels, according to the Lancet report on Health and Climate Change: Health at the Mercy of Fossil Fuels, raises the risk of disease, food insecurity, and other heat-related illnesses. What are the Report's Findings? Impact on Health: Climate change has an impact on the soc

Toppers

Search By Date

Newsletter Subscription
SMS Alerts