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DAILY NEWS ANALYSIS
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31 July, 2020
2 Min Read
According to a new study on Covid-19, pharmacological inhibition of PLpro blocks virus replication and also strengthens immune response in humans. Usually, when a virus attacks human cells, the infected body cells release messenger substances known as ‘type 1 interferons’ which attract the killer cells in human bodies. These killer cells kill the infected cells and save humans from getting sick.
When the novel coronavirus (SARS-CoV-2) enters a human cell, it hijacks the cell mechanism and fights back by letting the human cell produce PLpro. PLpro is a protein which suppresses the development of type 1 interferons. Due to this, killer cells are not informed about the infection. Hence, PL pro plays a crucial role in the replication of the virus.
Significance of the Research: Researchers can now monitor these processes in cell culture (artificial environment). By blocking PLpro, virus production can be controlled. In the absence of the PLpro, type 1 interferons will be released informing the killer cells and thus, strengthening the innate immune response of the human cells.
Source: TH
05 Apr, 26
A year after tensions arising from Operation Sindoor, India and Azerbaijan have taken steps to restore and normalise bilateral relations. The 6th round of Foreign Office Consultations, held in Baku, marked the first such engagement since 2022, signaling renewed diplomatic momentum. Recent Diplomatic Engagement During the consultations, bo
04 Apr, 26
The India–Australia Economic Cooperation and Trade Agreement has completed four years since its signing. Both countries now aim to build on this progress through strengthened collaboration and ambitious targets, including reaching AUD 100 billion in bilateral trade by 2030. What is the India–Australia Economic Cooperation and Tra
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A recent report by the Association for Democratic Reforms (ADR) analyses donations of ?20,000 or more declared to the Election Commission of India (ECI) by national political parties for FY 2024–25, highlighting transparency and accountability in political financing. Key Findings Massive Funding Surge Total donations to nationa
03 Apr, 26
Maritime chokepoints are narrow channels along global shipping routes where maritime traffic is concentrated. These points are geopolitically and economically critical, as they handle a large proportion of global trade, especially energy shipments. Current Relevance Over two-thirds of seaborne energy trade passes through a handful o
01 Apr, 26
Following the launch of Operation Epic Fury (U.S.) and Operation Roaring Lion (Israel), the geopolitical landscape has shifted fundamentally with the confirmed death of Iran’s Supreme Leader, Ayatollah Ali Khamenei.Iran retaliated through Operation True Promise 4, launching missile attacks against Israel and nearby Gulf states. The escala
05 Apr,2026
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