India’s First DNA Vaccine for Dengue

The first and only Dengue Fever DNA vaccine candidate in India has been created by scientists at India's National Centre for Biological Sciences in partnership with nine other institutions in India, Africa, and the US.
In early tests on mice, the candidate elicited a potent immune response and increased survival rates following illness exposure.

About Dengue Vaccine

The four strains of dengue are DEN-1, DEN-2, DEN-3, and DEN-4. The most prevalent strain in India is DEN-2. Dengue vaccines are challenging to produce since they must be effective against all 4 strains.
Only two dengue vaccinations have been given the go-ahead as of yet.
Sanofi, a French pharmaceutical firm, produces Dengvaxia. However, it can only be used by those who have already experienced Dengue or who reside in a region where the bulk of the population has already contracted the disease. This vaccine may raise the risk of developing severe dengue in those who have never had the infection.
Qdenga: Made by the Japanese business Takeds, it can be used by those without a history of infection.

A DNA vaccine is what?

A DNA vaccine is a type of vaccination that stimulates an immune response using a short bit of DNA from a pathogen, such as a virus or bacterium, that codes for a particular antigen (a molecule that causes an immunological response).
Direct injection of the DNA into the body's cells causes the cells to get instructions to create the antigen.
After then, the immune system identifies the antigen as foreign and launches an immunological reaction against it, aiding in the development of pathogen immunity.
Third-generation vaccines are DNA vaccines.
The DNA-based COVID-19 vaccine ZyCoV-D is the first of its kind in the world and was developed exclusively in India.

About Dengue

The viral disease transmitted by mosquitoes that spreads the fastest worldwide is dengue.
The World Health Organization (WHO) reports that roughly 2.5 billion people live in dengue-endemic countries and that there are an estimated 50 million dengue illnesses per year.
Dengue places a heavy financial, social, and health impact on those living in endemic areas.

Dengue affects people at all social strata, although the cost may be greater for the poorest who live in areas with poor solid waste management and water infrastructure, as well as where the principal vector, Aedes aegypti, can thrive.

Source: The Hindu

Join Our Telegram

Proton Beam Therapy

Indo-German Relations

World bank logistic performance index 2023

28 Apr, 23
SHARE

India is now ranked 38th out of 139 nations in the Logistic Performance Index (LPI) 2023 of the World Bank. From its previous rankings of 44th in 2018 and 54th in 2014, this is a notable improvement. Earlier, the Logistics Ease Across Different States (LEADS) Report 2022 was published by the Ministry of Commerce and Industry. About Logi

Smuggling of Gold

28 Apr, 23
SHARE

Airports discovered more than 63% of this illegal gold. The Department of Revenue Intelligence recently conducted the Golden Dawn Operation across India, seizing 101.7 kg of illegal gold valued at Rs 51 crore. Despite the fact that India receives a legal import of about 800-1,000 tonnes of gold each year, the illicit market is thought to be

India-Thailand Relations

27 Apr, 23
SHARE

Both parties expressed satisfaction with the ongoing bilateral defence cooperation at the 8th India-Thailand Defence Dialogue, which was held in Bangkok, Thailand. Cultural ties and mutual cooperation that have been shaped by thousands of years of lasting historical and cultural ties characterise India and Thailand relations. Highlight

Translocation of Elephants

27 Apr, 23
SHARE

The Kerala government's appeal of the order of the Kerala High Court is rejected by the Supreme Court. The Kerala government's appeal against the Kerala High Court's directive to move Arikomban (Wild Elephant), the "rice tusker" of Munnar, to the Parambikulam tiger reserve was recently dismissed by the Supreme Court.

Global Buddhist Summit

26 Apr, 23
SHARE

Global Buddhist Summit In order to improve diplomatic and cultural ties with other nations, the Ministry of Culture recently organised the First Global Buddhist Summit 2023 in collaboration with the International Buddhist Confederation (IBC). About the summit "Responses to Contemporary Challenges: Philosophy to Praxis" is